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Updated: Jul 18, 2026
14:53
Intra-Arterial Delivery of Neural Stem Cells to the Rat and Mouse Brain: Application to Cerebral Ischemia
Published on: June 26, 2020
Current concepts in adult stem cell therapy for stroke
Dah-Ching Ding1, Woei-Cherng Shyu, Shinn-Zong Lin
1Graduate Institute of Medical Science, School of Medicine, Tzu Chi University, and Neuro-Medical Scientific Center, Buddhist Tzu-Chi General Hospital, Hualien, Taiwan.
Current Medicinal Chemistry
|December 16, 2006
Summary
Adult stem cell therapies show promise for treating acute ischemic stroke when traditional treatments are inaccessible. Research is exploring various adult stem cell sources for effective stroke recovery strategies.
Area of Science:
- Neuroscience
- Regenerative Medicine
- Cell Biology
Background:
- Acute ischemic stroke disrupts neuronal function and the blood-brain barrier, leading to disability.
- Current thrombolytic therapy is limited by restricted patient access.
- Alternative stroke treatment strategies are crucial for improving patient outcomes.
Purpose of the Study:
- To review current preclinical cell-based therapies for stroke.
- To focus on the application of adult stem cells in stroke treatment.
- To highlight the potential of stem cell transplantation for stroke recovery.
Main Methods:
- Literature review of preclinical experimental studies.
- Analysis of studies utilizing human stem cells from diverse adult sources.
- Focus on stem cell-derived therapies for cerebral infarction.
Main Results:
- Preclinical studies demonstrate the potential of various adult stem cell sources for stroke treatment.
- Stem cell transplantation is an emerging therapeutic strategy for neurological repair after stroke.
- Research indicates promising preclinical outcomes for stem cell applications in stroke models.
Conclusions:
- Adult stem cell therapies represent a promising avenue for future stroke treatment.
- Further preclinical research is warranted to optimize stem cell application in stroke.
- Stem cell-based approaches may offer new hope for patients with acute ischemic stroke.
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