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Updated: Jul 18, 2026

Electronic von Frey associated with the Mouse Grimace Scale to Assess Allodynia and Pain in Trypanosoma evansi-Infected Mice
Published on: July 19, 2024
Study on the antioxidant status of rats experimentally infected with Trypanosoma evansi
O H Omer1, H M Mousa, N Al-Wabel
1Department of Veterinary Medicine, College of Agriculture and Veterinary Medicine, Qassim University, Buraidah, Saudi Arabia. osamaom@hotmail.com
Abstract:
The antioxidant status of rats experimentally infected with Trypanosoma evansi isolated from a camel was studied using established parasitological, haematological and biochemical methods. The results indicated that infections in all rats resulted in a fulminating parasitaemia. Changes in blood parameters in T. evansi-infected rats indicated leukocytosis and a macrocytic hypochromic anaemia. A degree of anisocytosis was also observed. The activities of plasma glucose-6-phosphate dehydrogenase and glutathione peroxidase in whole blood of infected rats were significantly higher (p<0.05 and p<0.001, respectively) compared with control. No statistically significant difference was observed in the activity of superoxide dismutase in infected and control rats. Results obtained indicated that trypanosomosis caused oxidative stress and induced antioxidant enzymes.

