Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Investigating the nonlinear microbubble response to chirp encoded, multipulse sequences.

Kevin Chetty1, Joseph V Hajnal, Robert J Eckersley

  • 1Imaging Sciences Department, Imperial College, London, UK.

Ultrasound in Medicine & Biology
|December 16, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Real-Time Targeted Slice Reacquisition for Motion-Corrupted Fetal Diffusion MRI.

Magnetic resonance in medicine·2026
Same author

Normative volumetric growth modeling of the whole fetal body, placenta, and amniotic fluid for three-dimensional T2-weighted magnetic resonance imaging.

Pediatric radiology·2026
Same author

Neonatal brain structure, cognitively stimulating parenting and behavioural outcomes in preschool children with congenital heart disease and controls.

Scientific reports·2026
Same author

Prenatal air pollution exposure is associated with altered neurodevelopmental outcomes in early childhood.

The Journal of physiology·2026
Same author

Associations between neonatal brain structure and neurodevelopmental outcomes following very preterm birth.

Journal of perinatology : official journal of the California Perinatal Association·2026
Same author

From Offline to Inline Without Pain: A Practical Framework for Translating Offline MR Reconstructions to Inline Deployment Using the Gadgetron Platform.

Magnetic resonance in medicine·2026

This study explored ultrasound contrast microbubbles using modified models. Chirp encoded sequences improved signal-to-noise ratio (SNR) and reduced artifacts, enhancing ultrasound imaging quality.

Area of Science:

  • Nonlinear Acoustics
  • Ultrasound Contrast Agents
  • Biomedical Engineering

Background:

  • Ultrasound contrast microbubbles are crucial for diagnostic imaging.
  • Optimizing signal-to-noise ratio (SNR) and axial resolution is essential for microbubble-based ultrasound.
  • Nonlinear acoustic responses of microbubbles to complex pulse sequences require detailed investigation.

Purpose of the Study:

  • To investigate the nonlinear acoustic response of ultrasound contrast microbubbles to multipulse phase and amplitude modulated, chirp encoded sequences.
  • To quantify trade-offs between SNR and axial resolution for varying chirp parameters.
  • To develop methods for minimizing postprocessing artifacts in chirp-encoded ultrasound sequences.

Main Methods:

  • Utilized a modified Rayleigh-Plesset model for microbubble acoustic response simulation.

Related Experiment Videos

  • Employed multipulse phase and amplitude modulated, chirp encoded sequences.
  • Compared chirp pulse inverted amplitude modulated (chirp PIAM) sequences with short pulse PIAM sequences.

    • Main Results:

    • Quantified SNR and axial resolution trade-offs with differing chirp time-bandwidth products.
    • Demonstrated that increasing chirp length and reducing bandwidth improves SNR at the cost of resolution.
    • Showed chirp sequences preserve energy post-scattering, leading to improved processed SNR.
    • Reduced compression artifacts by tuning chirp center frequency/bandwidth and reversing sweep direction.

    Conclusions:

    • Chirp encoded sequences offer improved SNR and artifact reduction for ultrasound contrast microbubbles.
    • Optimizing chirp parameters and sequence design is key to balancing SNR and resolution.
    • Modified Rayleigh-Plesset modeling provides valuable insights into microbubble nonlinear acoustics for advanced imaging.