Related Experiment Video
Updated: Jul 18, 2026

Morphological and Functional Assessment of the Right Ventricle Using 3D Echocardiography
Published on: October 28, 2020
Failure of gated SPECT and echocardiography to detect large apical aneurysm secondary to hyperdynamic left
Mohammad-Reza Movahed1, John Vu, Paul Lizotte
1Division of Cardiology, Department of Medicine, University of California, Irvine Medical Center, Orange, CA 92868-4080, USA. mmovahed@uci.edu
Insights
This case highlights how standard imaging like echocardiography and gated SPECT can miss large apical aneurysms in coronary artery disease patients due to hyperdynamic walls, stressing the need for multiple imaging methods.
Area of Science:
- Cardiology
- Medical Imaging
- Cardiovascular Disease
Background:
- Coronary artery disease (CAD) and myocardial infarction (MI) significantly impact left ventricular function.
- Apical aneurysms are a potential complication following anterior myocardial infarction.
- Accurate assessment of ventricular function is crucial for managing patients with CAD.
Observation:
- A patient with a history of anterior MI and CAD presented with exertional angina.
- Angiography revealed multivessel disease and a large apical aneurysm.
- Echocardiography and gated SPECT imaging were performed to assess left ventricular function and ischemia.
Findings:
- Both echocardiography and gated SPECT failed to detect the large apical aneurysm.
- This failure was attributed to a hyperdynamic left ventricular wall at the aneurysm's neck.
- Multivessel coronary artery disease was confirmed.
Implications:
- Standard imaging modalities may not always detect apical aneurysms in specific patient profiles.
- The hyperdynamic nature of the ventricular wall can mask significant structural abnormalities.
- Utilizing multiple imaging modalities is essential for comprehensive left ventricular function assessment in CAD patients.
- This case underscores the need for careful interpretation and consideration of complementary imaging techniques.
Abstract:
We present a patient with a history of coronary artery disease and exertional angina after an acute anterior myocardial infarction. Angiography and ventriculography revealed multivessel coronary artery disease and a large apical aneurysm. Echocardiography and gated SPECT studies were performed for further evaluation of ischemia and assessment of left ventricular function. Gated SPECT and echocardiography failed to detect a large apical aneurysm due to a hyperdynamic left ventricular wall at the neck of the aneurysm. This case demonstrates the importance of using multiple imaging modalities in the evaluation of ventricular function in the setting of coronary artery disease.
Related Concept Videos
Aortic Regurgitation II: Clinical Features and Diagnostic Tests
Mitral Stenosis II: Clinical features and Diagnostic Tests
Imaging Studies for Cardiovascular System II:Types of Echocardiography
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for diagnosing...
Aneurysm II: Clinical Manifestations and Diagnostic Studies
Cardiomyopathy III: Hypertrophic Cardiomyopathy
Aortic Regurgitation I: Introduction
