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Orofacial dermal fillers: foreign body reactions, histopathologic features, and spectrometric studies
Adepitan A Owosho1, Elizabeth A Bilodeau2, John Vu3
1Resident, Oral and Maxillofacial Pathology, Department of Diagnostic Sciences, University of Pittsburgh School of Dental Medicine, Pittsburgh, PA, USA.
Objective:
The aim of this study is to assess the different histopathologic presentations of dermal filler materials-induced foreign body reactions by spectrometric analyses.
Study Design:
Sixteen cases of dermal filler foreign body reactions in the orofacial region were retrieved from the 2006-2013 period. The histologic features were evaluated and categorized into 5 groups (I to V). Unstained deparaffinized sections of representative tissue from one case in each of groups I to IV were sent for spectrometric analysis, along with samples of 2 popular dermal fillers (Juvéderm and Radiesse).
Results:
With the help of spectrometric analysis, we were able to correlate the histopathologic presentations with the specific type of dermal filler used.
