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Related Experiment Videos

[Retroperitoneal extraskeletal myxoid chondrosarcoma].

A Fornari1

  • 1Dipartimento di Scienze Biomediche ed Oncologia Umana, Università di Torino, Italy.

Pathologica
|December 21, 2006
PubMed
Summary
This summary is machine-generated.

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[Immunohistochemistry in thyroid needle aspiration samples].

Pathologica·2006

Extraskeletal myxoid chondrosarcoma, a rare soft tissue tumor, was identified in a kidney tumor. This case highlights the tumor's varied presentation and expression of neural markers.

Area of Science:

  • Oncology
  • Pathology
  • Genetics

Background:

  • Extraskeletal myxoid chondrosarcoma (EMC) is a rare soft tissue tumor with controversial immunophenotype.
  • The specific translocation t(9;22)(q22;q12) is highly characteristic of EMC.
  • EMC is often grouped with tumors of uncertain differentiation due to infrequent well-formed cartilage.

Observation:

  • A 75-year-old female presented with a large kidney tumor with extrarenal extension.
  • The tumor was located in the perirenal fat tissue.
  • Histological examination revealed a malignant mesenchymal tumor with myxoid and chondroid differentiation.

Findings:

  • The diagnosis of extraskeletal myxoid chondrosarcoma was confirmed.
  • The tumor showed focal positivity for NSE (neuron-specific enolase) via immunohistochemistry.

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  • This case presented a rare tumor location and extensive chondroid differentiation.

    • Implications:

    • The findings contribute to understanding the diverse presentation of EMC.
    • Immunohistochemical results support the expression of neural markers in EMC.
    • This case underscores the importance of considering EMC in the differential diagnosis of soft tissue tumors.