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Generating Acute and Chronic Experimental Models of Motor Tic Expression in Rats
Published on: May 27, 2021
Tic disorders in childhood
1Pediatric Neurology Division, Dalhousie University and IWK Health Centre, Halifax, Nova Scotia, Canada. jdooley@dal.ca
Insights
Managing tic disorders, like Tourette syndrome, is complex due to comorbidities and impact on well-being. Individualized treatment plans focusing on patient goals and acceptance are crucial for successful management.
Area of Science:
- Neurology
- Child Psychiatry
- Developmental Pediatrics
Background:
- Tic disorders present diagnostic clarity but pose significant management challenges.
- The impact of tics and associated comorbidities profoundly affects a child's quality of life.
- Family, peer, and educator acceptance is vital for patient well-being.
Purpose of the Study:
- To review the complexities in managing tic disorders, emphasizing challenges beyond diagnosis.
- To highlight the importance of individualized treatment strategies and patient-centered goal setting.
- To discuss the role of pharmacotherapy and non-pharmacological approaches in tic disorder management.
Main Methods:
- Literature review on the management of tic disorders.
- Analysis of diagnostic criteria and therapeutic challenges.
- Discussion of common comorbidities and their impact on treatment.
Main Results:
- Tic disorder diagnosis is typically history-based, but management is complicated by comorbidities like ADHD and OCD.
- Pharmacotherapy is often essential, requiring individualized approaches to medication selection and symptom prioritization.
- Patient-defined goals and realistic expectations are key, as complete tic resolution is often unattainable.
Conclusions:
- Effective tic disorder management necessitates a holistic approach, addressing both tics and comorbidities.
- Education and fostering acceptance among the patient's social circle are critical components of care.
- Long-term strategies to mitigate the lifelong impact of Tourette syndrome are essential for improving patient outcomes.
Abstract:
Despite our familiarity with tic disorders, their management remains challenging. The difficulty seldom relates to the diagnosis, which is usually based on the history, but rather in dealing with the impact of the tics and multiple comorbidities. The child and family must be educated and must be taught how to facilitate a positive attitude among others who come in contact with the patient. Knowledge and acceptance of the tics by other family members, peers, teachers, and coaches often become central to the child's well-being. Although many children can be managed without pharmacotherapy, medications are often central to achieving success. The goals of therapy and the appropriate choice of medication must be individualized. We are frequently challenged not only by the wide array of medication choices available but also by the decision of which symptom to treat first. The tics, despite being flamboyant, are often viewed by the child and family as less disabling than co-occurring conditions, such as attention-deficit hyperactivity disorder, obsessive-compulsiveness, or rage. Even when tics are the major issue, patients must define their goals for therapy. It is unreasonable to expect a complete resolution of tics and safety usually rules in favor of better tolerated but potentially less efficacious therapies. Developing strategies to minimize the lifelong impact of the multiple components of Tourette syndrome is an essential aspect of the care of these patients.
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