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Lab-on-a-chip devices for global health: past studies and future opportunities

Curtis D Chin1, Vincent Linder, Samuel K Sia

  • 1Department of Biomedical Engineering, Columbia University, New York, NY 10027, USA.

Lab on a Chip
|December 21, 2006
PubMed

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The cultivation of environmental microorganisms has long been hindered by the inability to replicate complex native conditions in vitro. The isolation chip (iChip) addresses this limitation by facilitating the growth of previously uncultivable microorganisms through in situ incubation. Designed for high-throughput microbial cultivation, the iChip comprises hundreds of microchambers, each capable of housing a single microbial cell. These microchambers are loaded with a mixture of molten agar and...