Is amelogenesis imperfecta an indication for renal examination?
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Updated: Jul 18, 2026

Micro-dissection of Enamel Organ from Mandibular Incisor of Rats Exposed to Environmental Toxicants
Published on: March 29, 2018
Lindsay Hunter1, Liam D Addy, Jeremy Knox
1Dental Health and Biological Sciences, Cardiff University, Wales College of Medicine, Cardiff, UK. hunterml@cardiff.ac.uk
Background:
The term 'amelogenesis imperfecta' (AI) describes a diverse group of hereditary conditions primarily affecting the quality and/or quantity of dental enamel.
Case Report:
This paper describes a case in which hypoplastic AI with delayed/failure of eruption of the permanent teeth was shown to be associated with renal calcification.
Conclusion:
Given the importance of the renal involvement, the authors suggest that paediatric dentists consider referring all children with this dental phenotype for renal ultrasound examination.
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