Hereditary benign intraepithelial dyskeratosis: a new case?

Area of Science:

• Oral pathology
• Dermatology
• Genetics

Background:

• Hereditary benign intraepithelial dyskeratosis (HBID) is a rare genetic disorder.
• First described in 1960, most cases originate from a North Carolina Indigenous community.

Observation:

• A Brazilian patient presented with clinical and histological features consistent with HBID.
• The patient exhibited asymptomatic oral and ocular lesions.

Findings:

• This case represents the first documented instance of HBID in South America.
• The oral lesions were clinically similar to other conditions like white sponge nevus.

Implications:

• This finding expands the known geographical distribution of HBID.
• Further investigation into the genetic etiology of HBID in diverse populations is warranted.