Related Experiment Video
Updated: Jul 9, 2026
Precision Ultrasound-guided Stem Cell Delivery for Vascular Repair in Aortic Diseases
Published on: June 20, 2025
Predictive value of ultrasonographic parameters in the treatment of oral vascular anomalies
Luís Otávio Pereira da Silva1, Victor Zanetti Drumond1, Sílvia Ferreira de Sousa1
1Department of Oral Surgery and Pathology, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Background:
Vascular anomalies are a heterogeneous group of lesions characterized by abnormalities in vasculogenesis. Sclerotherapy is a conservative modality for their management. Ultrasonography can guide sclerotherapy and provide prognostic parameters.
Patients And Methods:
This prospective, nonrandomized observational study was conducted between 2023 and 2025. Thirty-one patients with oral vascular anomalies underwent standardized clinical and ultrasonographic assessment. Individuals were submitted to sclerotherapy with 3% polidocanol under ultrasound guidance. Outcomes included lesion area/perimeter, echogenicity, and flow proportion per area. Nonparametric tests assessed differences over time, and effect sizes (ES) were calculated.
Results:
The median of lesion area decreased from 0.15 to 0.07 cm² (P < .001; ES = 0.85) and perimeter from 1.76 to 1.29 cm (P < .001; ES = 0.92). Echogenicity shifted toward isoechoic patterns (P < .05), while flow proportion showed no significant changes (P > .05). High-flow lesions showed greater reduction of median area than low-flow lesions (-0.20 vs -0.04 cm²; P < .05; ES = 0.48), but no variation in perimeter was observed comparing high and low flow lesions (P > .05). Baseline echogenicity did not predict the sclerotherapy response (P > .05). Sclerotherapy guided by ultrasound is a safe and effective treatment for oral vascular anomalies.
Conclusions:
Ultrasonographic parameters, particularly baseline vascular flow, offer prognostic value for treatment response, whereas echogenicity is less informative.