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Amphiphilic NO-donor antioxidants

Konstantin Chegaev1, Loretta Lazzarato, Barbara Rolando

  • 1Dipartimento di Scienza e Tecnologia del Farmaco, Università degli Studi di Torino, Via Pietro Giuria 9, 10125 Torino, Italy.

Chemmedchem
|December 22, 2006
PubMed
Summary

Novel amphiphilic nitric oxide (NO)-donor antioxidants were synthesized and tested. Their antioxidant and vasodilator activities were found to be modulated by their interaction with phospholipid layers, enhancing their therapeutic potential.

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