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Fluorescence, CD, and NMR studies on spantide, a bombesin and substance P antagonist
C Di Bello1, A Scatturin, G D'Auria
1Institute of Industrial Chemistry, University of Padova, Italy.
Biopolymers
|May 1, 1991
Abstract:
The conformational properties of spantide [(D-Arg, D-Trp, Leu) substance P] have been studied by fluorescence, CD, and nmr techniques. The fluorescence, CD, and nmr parameters in different solvents and in a micellar environment (SDS) are compared with the data collected for bombesin. A preliminary investigation on [D-Pro] spantide is also reported.