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Medulloblastoma in a child with Duchenne muscular dystrophy
Harsha Doddihal1, Rakesh Jalali
1Department of Radiation Oncology, 116 Tata Memorial Hospital, Parel, Mumbai, 400 012, India.
Materials And Methods:
A 7-year-old boy diagnosed with Duchenne muscular dystrophy (DMD) presented with clinical features of raised intracranial tension. A CT scan revealed an enhancing vermian mass extending on to the fourth ventricle, which was excised and reported to be medulloblastoma. The patient was treated with craniospinal radiotherapy but progressed after 6 months.
Discussion:
Neoplasms associated with DMD are rare and the present case may well be the first one with medulloblastoma. Interestingly, all neoplasms associated with DMD reported so far have been round cell tumors, which may lead to insights into their possible molecular associations.
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