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Updated: Jul 18, 2026

Facile Preparation of 4-Substituted Quinazoline Derivatives
Published on: February 15, 2016
Selective thin-layer chromatography of 4-R-1,2,4-triazoles
Yves Boland1, Anne Attout, Jacqueline Marchand-Brynaert
1Université Catholique de Louvain, Unité de Chimie des Matériaux Inorganiques et Organiques, Département de Chimie, Faculté des Sciences, Place Louis Pasteur 1, 1348 Louvain-la-Neuve, Belgium.
Abstract:
A convenient and selective TLC of 4-R-1,2,4-triazoles (Rtrz) and nitrogen containing aromatic rings is presented (molecules 1-11). This simple revelation method implies a complexation of heterocycles to Co(II) ions on a TLC plate, followed by a subsequent modification of the reduction potential which enables oxidation of Co(II) by permanganate.
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