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Clozapine-induced angioneurotic edema
Biswaranjan Mishra1, Saddichha Sahoo, Sukanto Sarkar
1Central Institute of Psychiatry, Ranchi 834 006, India. drasoy@gmail.com
Abstract:
Many prescribed drugs can cause cutaneous rashes and eruptions, which may present in various forms and severity. Most of these reactions are mild; however, the severe cases can lead to life-threatening complications. The most severe of these reactions may include angioedema, acute generalized exanthematous reactions, Stevens-Johnson syndrome and toxic epidermal necrolysis. We report two cases wherein the patients developed classical angioneurotic edema on clozapine therapy and improved rapidly when clozapine was stopped.
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