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Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting

Published on: May 1, 2015

Littoral cell angioma.

Craig Johnson¹, Manish Goyal, Ben Kim

¹Department of Diagnostic Radiology, Northeastern Ohio Universities College of Medicine-Canton Affiliated Hospitals, 2600 Sixth Street SW, Canton, OH 44710, USA. craig.m.johnson@dmu.edu

Clinical Imaging

|December 27, 2006

Summary

Littoral cell angioma (LCA) is a rare splenic tumor. This case highlights imaging features and successful laparoscopic splenectomy for this vascular neoplasm.

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Area of Science:

Radiology
Oncology
Pathology

Background:

Littoral cell angioma (LCA) is an exceptionally rare primary splenic tumor.
Limited information exists regarding the specific MRI and scintigraphic features of LCA.
Differentiating LCA from other splenic vascular tumors is clinically significant.

Observation:

A 54-year-old woman presented with a 7-cm splenic mass identified on CT scan.
Ultrasound (US)-guided biopsy confirmed the diagnosis of LCA.
The patient underwent successful laparoscopic splenectomy.

Findings:

Detailed CT, MRI, and US imaging characteristics of the splenic mass are described.
Technetium-99m-labeled red blood cell (Tc99m-RBC) scan findings are correlated with imaging.
Histologic and immunohistochemical findings provide definitive tumor characterization.

Implications:

This case contributes to the understanding of LCA imaging findings.
Accurate pre-operative diagnosis can guide appropriate surgical management.
Laparoscopic splenectomy is a viable treatment option for splenic LCA.