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Ulcerative keratitis associated with contact lens wear
M Jayahar Bharathi1, R Ramakrishnan, R Meenakshi
1Microbiology Research Centre, Tirunelveli, Tamil Nadu-627 001, India. jayahar@tvl.aravind.org
Indian Journal of Ophthalmology
|December 27, 2006
Summary
Contact lens wearers with microbial keratitis predominantly develop gram-negative bacterial infections. Pseudomonas aeruginosa was the most common pathogen, and contaminated contact lens storage cases pose a significant infection risk.
Area of Science:
- Ophthalmology
- Microbiology
- Infectious Diseases
Background:
- Contact lens (CL)-wear is associated with microbial keratitis.
- Understanding the microbiological profile is crucial for effective treatment and prevention.
Purpose of the Study:
- To investigate the microbiological characteristics of ulcerative keratitis in contact lens wearers.
- To identify common pathogens and risk factors associated with CL-related microbial keratitis.
Main Methods:
- A retrospective study of 35 patients with culture-proven CL-associated microbial keratitis.
- Microbiological evaluation of corneal scrapes and contact lens care products.
- Analysis of bacterial isolates, focusing on gram-negative bacilli and Pseudomonas aeruginosa.
Main Results:
- All 35 patients (100%) had gram-negative bacilli isolated from corneal scrapes.
- Gram-negative bacilli were also found in 100% of CL storage case wells and 17.14% of CL care solutions.
- Pseudomonas aeruginosa was the predominant isolate (71.43%) from infected eyes.
Conclusions:
- Gram-negative bacilli, particularly Pseudomonas aeruginosa, are the primary cause of microbial keratitis in contact lens wearers.
- Contaminated contact lens storage cases represent a significant risk factor for gram-negative bacterial infections in soft CL wearers.
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