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Updated: Jul 18, 2026
A Novel and Translational Rat Model of Concussion Combining Force and Rotation with In Vivo Cerebral Microdialysis
Published on: July 12, 2019
[Expression of c-myc protein on rats' brains after brain concussion]
Wei-Hua Fang1, Dong-Liang Wang, Feng Wang
1Department of forensic medicine, Wannan medical college, Wuhu 241001, China. weihua_3110@yahoo.com.cn
Objective:
To study the changes of expression of c-myc protein on rats' brains after brain concussion.
Methods:
sixty rats were randomly divided into brain concussion groups and control group. The expression of c-myc protein was microscopically observed by immunohistochemical method.
Results:
No expression of c-myc protein in control group were observed. However, positive expression of c-myc protein in some neurons was seen at 20 min after brain concussion, and reach to the peak at 8h after brain concussion and then decreased gradually.
Conclusion:
These findings suggest that the detection of c-myc protein could be an index of diagnosis of brain concussion.
