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Nonaromatic amidine derivatives as acylation catalysts.

Vladimir B Birman1, Ximin Li, Zhenfu Han

  • 1Department of Chemistry, Washington University, Campus Box 1134, One Brookings Drive, St. Louis, Missouri 63130, USA. birman@wustl.edu

Organic Letters
|December 29, 2006
PubMed
Summary

The catalytic activity of bicyclic amidines and isothioureas in acylation reactions depends on ring size. Diazabicyclononane (DBN) and its thia-analogue (THTP) are highly effective acylation catalysts.

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