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Updated: Jul 18, 2026

DNAzyme 10-23 - Based Nanomachines for Nucleic Acid Recognition
Published on: February 9, 2024
DNA nanodevices
Friedrich C Simmel1, Wendy U Dittmer
1Department of Physics and Center for Nanoscience, LMU Munich, Geschwister Scholl Platz 1, 80539 Munich, Germany. simmel@lmu.de
Abstract:
The molecular recognition properties of DNA molecules combined with the distinct mechanical properties of single and double strands of DNA can be utilized for the construction of nanodevices, which can perform ever more tasks with possible applications ranging from nanoconstruction to intelligent drug delivery. With the help of DNA it is possible to construct machinelike devices that are capable of rotational motion, pulling and stretching, or even unidirectional motion. It is possible to devise autonomous nanodevices, to grab and release molecules, and also to perform simple information-processing tasks.

