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Updated: Jul 18, 2026
11:31
'Bioluminescent' Reporter Phage for the Detection of Category A Bacterial Pathogens
Published on: July 8, 2011
Summary
The Antonine Plague, likely smallpox, devastated the Roman Empire from AD 165 to 180. Historical accounts by Galen provide evidence identifying this ancient epidemic.
Area of Science:
- Ancient History
- Epidemiology
- Medical History
Context:
- The Roman Empire experienced a severe epidemic during Marcus Aurelius' reign.
- The plague originated in Mesopotamia around AD 165-166 and spread rapidly.
- It persisted until at least AD 180, impacting numerous lives.
Purpose:
- To analyze historical accounts of a major Roman epidemic.
- To identify the causative agent of the plague based on clinical descriptions.
Summary:
- The Antonine Plague, a significant epidemic in the Roman Empire, is described in historical records.
- Physician Galen's observations of the disease, including its exanthema, are crucial.
- Evidence strongly suggests the plague was smallpox, particularly noting the hemorrhagic phase.
Impact:
- Provides a definitive identification of a major historical epidemic.
- Enhances understanding of disease spread and impact in antiquity.
- Contributes to the study of smallpox history and its early manifestations.
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