[Use of two-dimensional O'Farrell electrophoresis for studying polymorphism of blood proteins]

Blood plasma of 50 healthy volunteers was analyzed using two-dimensional electrophoresis by O'Farrell. After staining with Coomassie R-250 and subsequent silver treatment of gels 200 protein fractions were detected on typical electrophoregrams. About 20 groups, belonging to known polymorphic systems, were identified. Dissimilar types of proteins electrophoretic variants were found in the preparations studied.