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Surgical Approach, Challenges, and Resolutions for Uterus Transplantation in Rats
Published on: April 14, 2023
Human uterus retrieval from a multi-organ donor
Giuseppe Del Priore1, Jeanetta Stega, Krishen Sieunarine
1New York Downtown Hospital, New York-Presbyterian Health Care Partner, New York, NY 10038, USA. info@cancerandfertility.org
Obstetrics and Gynecology
|January 2, 2007
Summary
The human uterus can be successfully retrieved for transplantation using established organ donor protocols. This surgical technique ensures the uterus remains viable during cold ischemia for over 12 hours.
Area of Science:
- Reproductive medicine
- Transplant surgery
- Organ donation
Background:
- Uterus transplantation is a developing field for treating uterine factor infertility.
- Standardized protocols for organ retrieval are crucial for successful transplantation.
Purpose of the Study:
- To establish the feasibility of uterus retrieval for reproductive organ transplantation.
- To document the surgical technique for uterus procurement.
Main Methods:
- Participation in a local organ donor network over six months.
- Identification of multi-organ donors following established protocols.
- Uterus retrieval with specific consent, utilizing ovarian, uterine, or internal iliac vessels.
Main Results:
- Eight successful uterus retrievals were performed without complications from nine consented donors.
- Histological analysis confirmed no changes in the uterus during 12 hours of cold ischemia.
- The procurement utilized existing multi-organ donor network infrastructure.
Conclusions:
- The human uterus can be retrieved from local organ donor networks.
- Existing organ donation protocols are applicable for uterus retrieval.
- The surgical technique is viable for obtaining a uterus for transplantation.
