Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Molecular physiology of kainate receptors.

Physiological reviews·2001

Same author

ATP-mediated glia signaling.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2001

Same author

Learning motor synergies makes use of information on muscular load.

Learning & memory (Cold Spring Harbor, N.Y.)·2000

Same author

Two populations of kainate receptors with separate signaling mechanisms in hippocampal interneurons.

Proceedings of the National Academy of Sciences of the United States of America·2000

Same author

Purification and characterization of rat hippocampal CA3-dendritic spines associated with mossy fiber terminals.

FEBS letters·1999

Same author

Morphological changes associated with long-term potentiation.

Histology and histopathology·1998

Search research articles

Related Experiment Video

Updated: Jul 17, 2026

Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography

Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography

Published on: December 2, 2022

[Atypical macular coloboma: a case report].

J C López-García¹, J Buesa-Gómez, A Pardo-Saiz

¹Hospital Universitario Joan XXIII, Tarragona, España. javiercorsini@eresmas.com

Archivos De La Sociedad Espanola De Oftalmologia

|January 3, 2007

Summary

Atypical macular colobomata, not congenital infection, caused vision problems in a child exposed to varicella in utero. Negative serology supported this diagnosis.

More Related Videos

Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy

Published on: January 12, 2022

Related Experiment Videos

Last Updated: Jul 17, 2026

Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography

Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography

Published on: December 2, 2022

Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy

Published on: January 12, 2022

Area of Science:

Ophthalmology
Pediatric Ophthalmology
Medical Genetics

Background:

Maternal infections during pregnancy can lead to congenital abnormalities.
Varicella (chickenpox) infection in pregnancy poses risks to fetal development.
Retinochoroidal lesions in infants warrant thorough investigation for underlying causes.

Observation:

A 15-month-old boy presented with bilateral macular retinochoroidal lesions.
The child's mother had varicella infection during pregnancy.
Initial differential diagnosis included congenital chorioretinal infection.

Findings:

Serological tests for congenital infections were negative.
Clinical examination revealed features atypical for infectious scarring.
The macular lesions were ultimately diagnosed as atypical macular colobomata.

Implications:

This case highlights the importance of considering atypical macular colobomata in infants with suspected congenital infections.
Negative serology is crucial in differentiating infectious sequelae from developmental anomalies.
Accurate diagnosis is essential for appropriate management and genetic counseling.