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Invasive candidiasis in infants: experience from Saudi Arabia

K A Adam1, S al Rasheed

  • 1Department of Paediatrics, College of Medicine, Riyadh, Saudi Arabia.

Annals of Tropical Paediatrics
|January 1, 1991
PubMed

Insights

Invasive candidiasis in infants is rare in Saudi Arabia. This report highlights two cases, emphasizing predisposing factors and the need for increased physician awareness to improve diagnosis and treatment outcomes.

Area of Science:

  • Medical Mycology
  • Pediatric Infectious Diseases

Background:

  • Invasive candidiasis (IC) reports in infants are scarce, particularly in tropical regions and Saudi Arabia.
  • Candida species are a significant cause of healthcare-associated infections in neonates.

Observation:

  • Two cases of invasive candidiasis in Saudi infants are presented.
  • Clinical features and treatment responses were compared to international pediatric literature.

Findings:

  • Identified predisposing factors include prematurity, low birthweight, invasive procedures, prolonged hospitalization, and broad-spectrum antibiotic use.
  • Physician unawareness of these risk factors may contribute to diagnostic delays.

Implications:

  • Highlights the need for heightened clinical vigilance and awareness regarding infant invasive candidiasis in the region.
  • Emphasizes the critical importance of not overlooking Candida isolates from clinical specimens.

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