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Updated: Jul 17, 2026

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Optimization of the Retinal Vein Occlusion Mouse Model to Limit Variability
Published on: August 6, 2021
Histopathological study of a case with branch retinal vein occlusion
Tsuyoshi Kimura1, Atsushi Mizota, Emiko Adachi-Usami
1Department Ophthalmology and Visual Science, Graduate School of Medicine, Chiba University, Chiba, Japan.
Abstract:
A retinal specimen from a 68-year-old patient with glaucoma and branch retinal vein occlusion was examined by light and electron microscopy. The venous and arterial lumina were filled with erythrocytes, and many erythrocytes extravasated into the venous wall. We suggest that constant rubbing of endothelial cells of the occluded vein results in damage and erythrocyte extravasation was caused by diapedesis.
