Contrast-enhanced magnetic resonance angiography of persistent fifth aortic arch in children
Yumin Zhong1, Richard B Jaffe, Ming Zhu
1Department of Radiology, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, 1678 Dong Fang Road, Shanghai 200127, People's Republic of China. yumink@online.sh.cn
Insights
Contrast-enhanced magnetic resonance angiography (MRA) accurately diagnosed persistent fifth aortic arch in pediatric patients. MRA offers a safe, noninvasive alternative to traditional imaging methods like echocardiography and cine angiography.
Area of Science:
- Cardiovascular Imaging
- Pediatric Cardiology
- Radiology
Background:
- Congenital aortic arch anomalies pose diagnostic challenges.
- Echocardiography has limited visualization of great vessels; cine angiography requires invasive cardiac catheterization and radiation.
- Contrast-enhanced magnetic resonance angiography (MRA) offers a noninvasive imaging solution.
Purpose of the Study:
- To assess the diagnostic utility of contrast-enhanced MRA for persistent fifth aortic arch.
- To compare the accuracy of MRA against echocardiography and cine angiography.
Main Methods:
- Contrast-enhanced MRA was performed in four pediatric patients with suspected persistent fifth aortic arch.
- MRA findings were compared with echocardiography and confirmed by cine angiography and surgical outcomes.
Main Results:
- Echocardiography provided uncertain or incorrect diagnoses in all four patients.
- Contrast-enhanced MRA accurately diagnosed persistent fifth aortic arch with fourth aortic arch interruption in all four cases.
- MRA clarified echocardiographic findings and identified the anomaly definitively.
Conclusions:
- Contrast-enhanced MRA is a safe, accurate, and rapid imaging technique for evaluating persistent fifth aortic arch.
- MRA may replace conventional cine angiography for diagnosing this condition.
- Cardiac catheterization can be reserved for complex congenital heart disease and hemodynamic assessment.
Background:
Cine angiography and echocardiography have been utilized to diagnose congenital aortic arch anomalies. However, the visualization of great vessels by echocardiography is limited, while cine angiography requires cardiac catheterization with ionizing radiation. Contrast-enhanced magnetic resonance angiography (MRA) is a noninvasive modality suitable for visualization of congenital aortic arch anomalies.
Objective:
To evaluate the utility of contrast-enhanced MRA in the diagnosis of persistent fifth aortic arch, a rare congenital aortic arch anomaly, and to compare the diagnostic accuracy of MRA with that of echocardiography and cine angiography.
Materials And Methods:
In four pediatric patients, contrast-enhanced MRA studies were performed for diagnosing persistent fifth aortic arch. The findings of MRA were compared with echocardiographic findings and confirmed by cine angiography and operation.
Results:
Transthoracic surface echocardiography noted an aberrant vessel arising from the ascending aorta in two of four patients; the etiology of this vessel was uncertain. In the other two patients a diagnosis of coarctation was made. Of the four patients, only one was diagnosed with interruption of the aortic arch. Contrast-enhanced MRA clarified uncertain echocardiographic findings, enabling the correct diagnosis of persistent fifth aortic arch with fourth aortic arch interruption in all four patients.
Conclusion:
Contrast-enhanced MRA is a safe, accurate, and fast imaging technique for the evaluation of persistent fifth aortic arch and may obviate the need for conventional cine angiography. Cardiac catheterization may be reserved for some types of complicated congenital heart disease and for obtaining hemodynamic information.
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