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A Clinical Trial Assessing the Safety, Efficacy, and Delivery of Olive-Oil-Based Three-Chamber Bags for Parenteral Nutrition
Published on: September 20, 2019
Wernicke's encephalopathy during parenteral nutrition
Francesco Francini-Pesenti1, Filippo Brocadello, Stefania Famengo
1Clinical Nutrition Unit, Department of Clinical and Experimental Medicine, Azienda Ospedaliera, Padua, Italy. francescofrancini@yahoo.com
JPEN. Journal of Parenteral and Enteral Nutrition
|January 5, 2007
Summary
Thiamine deficiency can cause Wernicke
Area of Science:
- Neurology
- Nutritional Science
Background:
- Thiamine deficiency impacts multiple body systems.
- Wernicke's encephalopathy is linked to alcoholism, hyperemesis gravidarum, and inadequate IV feeding.
Observation:
- A 66-year-old man developed Wernicke's syndrome during parenteral nutrition post-pancreatitis surgery.
- Symptoms included neurological deficits and thrombocytopenia, appearing after using industrial nutrition bags without vitamin supplementation.
Findings:
- Neurological signs and platelet count normalized with intravenous thiamine (100 mg daily).
- MRI scans showed resolution of brain lesions.
Implications:
- Highlights risks associated with industrial parenteral nutrition bag management.
- Suggests a potential link between thiamine deficiency and thrombocytopenia.
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