Related Experiment Video
Updated: Jul 17, 2026

Chinese Herbal Retention Enema for the Treatment of Ulcerative Colitis
Published on: May 16, 2025
Pattern of relapses in Iranian patients with ulcerative colitis. A prospective study
Nasser Ebrahimi Daryani1, Mohammad Bashashati, Setareh Aram
1Department of Gastroenterology and Hepatology, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran. nebrahim@sina.tums.ac.ir
Background:
The pattern of relapses in patients with ulcerative colitis (UC) has a significant role in taking decisions about the therapy and the follow up of patients. This study is designed to find out the pattern, time and severity of relapses in Iranian patients with UC.
Method:
From 1991 to 2003, a period of 13 years, the pattern of relapses in 163 patients with UC who had been admitted to a private referral gastroenterology clinic in Iran were evaluated.
Results:
163 patients (58.3% female, 41.7% male) were included, aged from 17 to 74 years with mean age of 38.9 ± 12.3 years. Mean follow up time was 52.7 ± 41.4 months (ranges 12 and 155 months). Mean relapse chance was 0.028 ± 0.036 for each patient in every month (ranges 0-0.21). The mean time from the initial attack to the first relapse was 23.8 ± 22.5 months, which was not the same in patients with different primary disease severity (p = 0.03).
Conclusion:
The time and severity of the relapses relate to the severity of UC. Iranian patients have a milder course of the disease.
Related Concept Videos
Inflammatory Bowel Disease IV: Clinical Manifestations
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory Bowel Disease II: Ulcerative Colitis
Inflammatory Bowel Disease I: Introduction
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the colonic...
Drugs for Treatment of Ulcerative Colitis in IBD