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Prism adaptation to optical deviation alleviates pathologic pain.

M Sumitani1, Y Rossetti, M Shibata

  • 1Department of Acute Critical Medicine, Osaka University, Graduate School of Medicine, Osaka, Japan.

Neurology
|January 11, 2007
PubMed
Summary
This summary is machine-generated.

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Prism adaptation (PA) can alleviate complex regional pain syndrome (CRPS) by modifying visual input. This study shows that adapting vision towards the unaffected side reduced pain, suggesting PA as a potential treatment for CRPS.

Area of Science:

  • Neuroscience
  • Pain Research
  • Vision Science

Background:

  • The interdependence of human visual and somatosensory systems is well-established.
  • Previous research demonstrated that somatosensory changes can alter visual perception.
  • This study investigates the converse: if altered visual experience can modify the perception of pathological pain.

Observation:

  • Five patients with complex regional pain syndrome (CRPS) underwent prism adaptation (PA) with visual displacement towards their unaffected side.
  • Subjects performed a target-pointing task daily for two weeks while wearing prismatic goggles.
  • Pain intensity and visual subjective body-midline judgment were assessed at pre-test, immediately after initial PA exposure, and after 14 days of PA.

Findings:

  • Prism adaptation (PA) towards the unaffected side significantly alleviated pathological pain and other CRPS symptoms.

Related Experiment Videos

  • No immediate analgesic effect was observed after the first PA exposure.
  • Sham PA and adaptation towards the affected side showed no improvement, with the latter exacerbating pain.

    • Implications:

    • Visual input can modulate pathological pain perception.
    • Prism adaptation demonstrates a direction-specific and reproducible effect on CRPS symptoms.
    • PA shows potential as a non-invasive cognitive treatment for complex regional pain syndrome.