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Updated: Jul 17, 2026

Epidural Intracranial Pressure Measurement in Rats Using a Fiber-optic Pressure Transducer
Published on: April 25, 2012
CSF pressure assessed by lumbar puncture agrees with intracranial pressure
N Lenfeldt1, L-O D Koskinen, A T Bergenheim
1Department of Clinical Neuroscience, Umeå University, S-901 85 Umeå, Sweden. niklas.lenfeldt@neuro.umu.se
Abstract:
The accuracy of estimating intracranial pressure in brain tissue (ICP(BT)) via lumbar space was investigated using preset pressure levels in the interval 0 to 600 mm H(2)O in patients with communicating hydrocephalus. Lumbar space ICP correlated excellently to ICP(BT), demonstrated by a measured mean difference of 10 mm H(2)O (0.75 mm Hg) and a regression coefficient of 0.98. The concurrence supports the lumbar puncture as an accurate technique to determine ICP in patients with communicating CSF systems.
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