Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Early clinical experience with a minute ventilation sensor DDDR pacemaker.

G Vanerio1, S Patel, E Ching

  • 1Department of Cardiology, Cleveland Clinic Foundation, Ohio 44195.

Pacing and Clinical Electrophysiology : PACE
|November 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Declining Use of Corticosteroids for Crohn's Disease Has Implications for Study Recruitment: Results of a Pilot Randomized Controlled Trial.

Journal of the Canadian Association of Gastroenterology·2021
Same author

Transmission of Donor-Derived <i>Trypanosoma cruzi</i> and Subsequent Development of Chagas Disease in a Lung Transplant Recipient.

Case reports in infectious diseases·2017
Same author

Venovenous extracorporeal membrane oxygenation in patients with atrial septal defects.

Perfusion·2014
Same author

Active fixation mechanism complicates coronary sinus lead extraction and limits subsequent reimplantation targets.

Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing·2012
Same author

A report of ten cases of tetanus.

Medical bulletin. United States. Army. Forces in the European Theater. Office of the Theater Chief Surgeon·2010
Same author

Meta-analysis: yield of diagnostic tests for coeliac disease in dyspepsia.

Alimentary pharmacology & therapeutics·2009
Same journal

Dual Coronary Sinus Lead Strategy to Avoid Tricuspid Valve Traversal in Biventricular Pacing.

Pacing and clinical electrophysiology : PACE·2026
Same journal

A Case of Permanent Pacemaker Implantation via the Epicardial Approach Using the 3830 Lead in an 11-Day-Old Neonate (With Follow-Up of the Above Case).

Pacing and clinical electrophysiology : PACE·2026
Same journal

Cryoballoon Versus Radiofrequency Ablation for Persistent Atrial Fibrillation: Meta-Analysis of Randomized Trials.

Pacing and clinical electrophysiology : PACE·2026
Same journal

Tilt Test Duration in Suspected Vasovagal Syncope: Temporal Patterns and Diagnostic Yield in Patients From Central China.

Pacing and clinical electrophysiology : PACE·2026
Same journal

Combined Leadless Pacing and Subcutaneous ICD Therapy in Long QT Syndromes.

Pacing and clinical electrophysiology : PACE·2026
Same journal

Association of Anesthesia Modality With Procedural Parameters and Clinical Outcomes in PVI for Atrial Fibrillation.

Pacing and clinical electrophysiology : PACE·2026
See all related articles

The META DDDR pacemaker uses minute ventilation sensing to prevent tracking of rapid atrial rhythms. Mode switching to VVIR occurred in 57% of patients, effectively managing tachyarrhythmias but requiring careful programming.

Area of Science:

  • Cardiology
  • Biomedical Engineering
  • Medical Devices

Background:

  • The META DDDR pacemaker incorporates a novel minute ventilation sensor using transthoracic impedance.
  • This sensor influences key pacing parameters like AV delay and postventricular atrial refractory period (PVARP).
  • Appropriate PVARP selection is crucial for distinguishing physiological rhythms from non-physiological tachycardias.

Purpose of the Study:

  • To evaluate the efficacy and behavior of the META DDDR pacemaker in patients with various cardiac conditions.
  • To assess the performance of the automatic mode switching feature in preventing tracking of atrial tachyarrhythmias.
  • To determine the impact of PVARP programming on pacemaker function and patient outcomes.

Main Methods:

  • A study was conducted on 28 patients (mean age 65 ± 13 years) with sinus node dysfunction, AV junction ablation, or AV block, implanted with the META DDDR pacemaker.

Related Experiment Videos

  • The study monitored mode switching events during stress tests and 24-hour Holter recordings.
  • Patient follow-up included assessment of pacemaker mode (DDDR, DDD, VVIR) and reprogramming decisions.

    • Main Results:

    • Mode switching to VVIR was observed in 57% of patients.
    • Episodes of mode switching were linked to paroxysmal atrial tachyarrhythmias (PAT) and sinus tachycardia during stress tests and Holter monitoring.
    • At follow-up, 20 of 26 patients remained in DDDR mode, with some reprogrammed to DDD or VVIR.

    Conclusions:

    • The META DDDR pacemaker's mode switching is a sensitive, albeit not highly specific, method for preventing rapid tracking of atrial tachyarrhythmias.
    • Careful programming of PVARP is essential for optimal mode switching performance.
    • Further algorithm refinements are necessary to enhance the pacemaker's overall effectiveness.