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Myelomatous pleural effusion.

Sharmila Ghosh1, R Gopal, S H Advani

  • 1Department of Pathology, Asian Institute of Oncology, SL Raheja Hospital, Rahaeja Hospital Marg, Mahim, Mumbai.

The Journal of the Association of Physicians of India
|January 11, 2007
PubMed
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A rare case of myelomatous pleural effusion in multiple myeloma is presented. This effusion, diagnosed by cytology and biopsy, initially responded to chemotherapy but recurred.

Area of Science:

  • Hematology
  • Oncology

Background:

  • Multiple myeloma, a plasma cell malignancy, rarely presents with serous effusions.
  • Myelomatous pleural effusion, specifically, is an exceedingly rare complication.

Observation:

  • A 38-year-old female diagnosed with multiple myeloma developed pleural effusion.
  • The effusion's myelomatous origin was confirmed via cytology and pleural biopsy.

Findings:

  • The pleural effusion demonstrated an initial positive response to chemotherapy.
  • Despite initial treatment, the myelomatous pleural effusion subsequently recurred.

Implications:

  • This case highlights the rare occurrence of myelomatous pleural effusion in multiple myeloma.
  • It underscores the importance of considering neoplastic causes for effusions in myeloma patients, even with initial treatment response.

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