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Related Experiment Video

Updated: Jul 17, 2026

Induction of Paralysis and Visual System Injury in Mice by T Cells Specific for Neuromyelitis Optica Autoantigen Aquaporin-4

Induction of Paralysis and Visual System Injury in Mice by T Cells Specific for Neuromyelitis Optica Autoantigen Aquaporin-4

Published on: August 21, 2017

Optic neuritis is nothing to sneeze at.

Michael S Vaphiades¹, Jacob J Yunker, Glenn H Roberson

¹Departments of Ophthalmology, University of Alabama at Birmingham, Birmingham, Alabama 35233, USA.

Survey of Ophthalmology

|January 11, 2007

Summary

A sphenoid sinus mucocele caused sudden vision loss, mimicking optic neuritis. Surgical drainage of the mucocele significantly restored the patient's vision.

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Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients

Published on: April 14, 2014

Area of Science:

Ophthalmology
Neurosurgery
Otolaryngology

Background:

Optic neuritis is a common cause of acute visual loss.
Sphenoid sinus mucoceles are rare benign cystic masses that can cause significant complications due to their proximity to critical neurovascular structures.

Observation:

A 36-year-old man presented with acute left eye visual loss.
Cranial MRI revealed a sphenoid sinus mucocele compressing the left optic nerve via extension into the anterior clinoid process.

Findings:

Endoscopic marsupialization of the sphenoid sinus mucocele was performed.
The patient experienced marked improvement in vision following the surgical intervention.

Implications:

Sphenoid sinus mucocele should be considered in the differential diagnosis of optic neuritis.
Endoscopic surgery is an effective treatment for vision-threatening sphenoid sinus mucoceles.