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Updated: Jul 17, 2026
07:25
A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
Published on: March 6, 2018
[Prostate cancer in the elderly patient]
1Department of urology, University of Vienna, Xähringer Gürtel 18-20, 1090 Vienna, Autriche.
Annales D'Urologie
|January 12, 2007
Summary
Elderly men diagnosed with prostate cancer benefit from considering radical prostatectomy, a treatment offering excellent outcomes and long-term disease control. Age is a critical factor in therapeutic decisions for prostate cancer.
Area of Science:
- Oncology
- Geriatric Medicine
- Urology
Context:
- Cancer disproportionately affects individuals aged 65 and older.
- Increased life expectancy and prostate specific antigen (PSA) screening have led to more elderly men diagnosed with prostate cancer.
- Age is a significant prognostic factor in prostate cancer treatment decisions, alongside PSA level and Gleason score.
Purpose:
- To evaluate the role of radical prostatectomy in elderly men diagnosed with prostate cancer.
- To discuss the prognostic significance of age in prostate cancer management.
- To explore treatment options for elderly men, including expectant management for low-grade disease.
Summary:
- Prostate cancer diagnosis is rising in elderly men due to increased life expectancy and PSA screening.
- Radical prostatectomy in modern practice offers low morbidity, excellent clinical outcomes, and long-term disease control for prostate cancer.
- Expectant management is an option for screening-detected low-grade prostate cancer, with therapy initiated upon disease progression.
Impact:
- Highlights the importance of considering radical prostatectomy for elderly men with prostate cancer.
- Emphasizes age as a crucial prognostic factor in treatment decision-making for prostate cancer.
- Suggests that undertreatment of elderly prostate cancer patients may lead to loss of life years.
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