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Related Experiment Video

Updated: Jul 17, 2026

Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection
04:04

Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection

Published on: August 15, 2025

Bilateral macrostomia as an isolated pathology.

Arnaud Gleizal1, Derrick C Wan, Arnaud Picard

  • 1Department of Oral and Maxillofacial Surgery, Hôpitaux Nord, Lyon, France.

The Cleft Palate-Craniofacial Journal : Official Publication of the American Cleft Palate-Craniofacial Association
|January 12, 2007
PubMed
Summary

Bilateral congenital macrostomia, a rare condition, often presents as an isolated defect and typically results in normal function. Surgical repair requires careful planning using external landmarks due to the absence of a contralateral side.

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Area of Science:

  • Plastic Surgery
  • Craniofacial Surgery
  • Congenital Malformations

Background:

  • Congenital macrostomia involves a lateral orofacial cleft affecting the first branchial arch.
  • Bilateral congenital macrostomia is a rare condition, with limited documented cases.
  • Understanding its characteristics is crucial for effective management.

Purpose of the Study:

  • To compare the clinical experience of bilateral congenital macrostomia with existing world literature.
  • To analyze the presentation, treatment, and outcomes of bilateral macrostomia.

Main Methods:

  • Retrospective analysis of 20 bilateral congenital macrostomia cases (6 from local units, 14 from literature).
  • Comparison with unilateral macrostomia cases reported post-1954.

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Last Updated: Jul 17, 2026

Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection
04:04

Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection

Published on: August 15, 2025

  • Evaluation of surgical techniques (linear sutures, Z-plasty) and outcomes.

    • Main Results:

    • Bilateral macrostomia is frequently isolated, unlike unilateral forms which often have associated deformities.
    • Defect size tends to be larger in bilateral cases compared to unilateral.
    • Functional outcomes (feeding, speech, mouth opening) were consistently normal, with symmetrical clefts.

    Conclusions:

    • The etiology of bilateral congenital macrostomia remains unclear.
    • Despite being often isolated, bilateral macrostomia poses surgical challenges due to the lack of a symmetrical reference.
    • Surgical repair necessitates the use of extraoral landmarks for accurate commissure positioning.