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Related Experiment Video

Updated: Jul 17, 2026

Echocardiographic Approaches and Protocols for Comprehensive Phenotypic Characterization of Valvular Heart Disease in Mice
12:12

Echocardiographic Approaches and Protocols for Comprehensive Phenotypic Characterization of Valvular Heart Disease in Mice

Published on: February 14, 2017

Echocardiographic evaluation of ventricular function in mice.

Jeffrey N Rottman1, Gemin Ni, Michael Brown

  • 1Division of Cardiovascular Medicine, Department of Internal Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-6300, USA. jeff.rottman@vanderbilt.edu

Echocardiography (Mount Kisco, N.Y.)
|January 12, 2007
PubMed
Summary

Echocardiography in mice is crucial for studying cardiac disease. This review details ventricular function measurement in conscious and anesthetized mice, aiding cardiovascular research.

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Area of Science:

  • Cardiovascular Biology
  • Medical Imaging
  • Animal Models

Background:

  • Ventricular dysfunction is central to cardiac disease.
  • Mice are vital models in cardiovascular research.
  • Echocardiography is a key tool for assessing mouse cardiac function.

Purpose of the Study:

  • To review echocardiographic methods for measuring ventricular function in mice.
  • To contrast assessments in conscious versus anesthetized conditions.
  • To provide normal echocardiographic values for C57BL/6 mice.

Main Methods:

  • Echocardiographic assessment of left ventricular function in mice.
  • Comparison of techniques for conscious and anesthetized imaging.
  • Evaluation of diastolic function using echocardiography.

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Transthoracic Echocardiography in Mice
08:09

Transthoracic Echocardiography in Mice

Published on: May 28, 2010

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Last Updated: Jul 17, 2026

Echocardiographic Approaches and Protocols for Comprehensive Phenotypic Characterization of Valvular Heart Disease in Mice
12:12

Echocardiographic Approaches and Protocols for Comprehensive Phenotypic Characterization of Valvular Heart Disease in Mice

Published on: February 14, 2017

Transthoracic Echocardiography in Mice
08:09

Transthoracic Echocardiography in Mice

Published on: May 28, 2010

Main Results:

  • Echocardiography can assess ventricular function in both conscious and anesthetized mice.
  • Advancements enable improved imaging in conscious mice.
  • Normal values for C57BL/6 strain are provided.

Conclusions:

  • Echocardiography is a versatile tool for mouse cardiac research.
  • Methodological choices impact ventricular function assessment.
  • Further advancements aid in understanding cardiac disease pathophysiology.