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Updated: Jul 17, 2026

An Orthotopic Sciatic Nerve Xenograft for Neurofibromatosis Type 1 Neurofibromas
Published on: October 10, 2025
Modified wise pattern skin reduction for plexiform neurofibromatosis of the breast
Vamsi R Velchuru1, Sandesh G Satish, Raman Guruswamy
1Department of Surgery, James Paget Healthcare NHS Trust, Great Yarmouth, United Kingdom. velchuru@hotmail.com
Abstract:
Von Recklinhausen's neurofibromatosis is an autosomal dominant condition occurring typically with café au lait patches, axillary freckling, multiple fibromata, and Lisch nodules. We present a case of a 36-year-old female who presented with severe neurofibromatosis involving the lower half of the breast. The patient was not keen on mastectomy and pedicle flap reconstruction. A modified wise pattern incision was employed to remove the lower half of the breast and neurofibromatosis leading to a reasonable result.
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