Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Nerve agents.

Jonathan Newmark1

  • 1Deputy Joint Program Executive Officer for Medical Systems, Joint Program Executive Office for Chemical/Biological Defense, Falls Church, Virginia 22041-3203, USA. jonathan.newmark@us.army.mil

The Neurologist
|January 12, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Therapy for acute nerve agent poisoning: An update.

Neurology. Clinical practice·2019
Same author

Sulfur mustard: a liquid, not a gas.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2011
Same author

Case report: Long-term cognitive sequelae of sarin exposure.

Neurotoxicology·2009
Same author

Neurological problems of famous musicians: the classical genre.

Journal of child neurology·2009
Same author

Liquid sulfur mustard exposure.

Military medicine·2007
Same author

Vitamin D and Parkinson's disease--a hypothesis.

Movement disorders : official journal of the Movement Disorder Society·2007
Same journal

A Narrative Review of Amyloid-β Monoclonal Antibodies for Alzheimer Disease: How Amyloid Species Engagement May Affect Clinical Outcomes.

The neurologist·2026
Same journal

Artificial Intelligence in the Prehospital Stage of Stroke: Can Virtual Assistants Optimize Triage?

The neurologist·2026
Same journal

Looking Beyond the Midline: An Uncommon Etiology of Internuclear Ophthalmoplegia of Abduction Due to Cerebral Venous Thrombosis.

The neurologist·2026
Same journal

Commentary: Cervical Artery Dissection and Chiropractic Cervical Manipulation: Clarifying Association, Mechanism, and Interpretation.

The neurologist·2026
Same journal

Acute Spinal Cord Infarct Secondary to Fibrocartilaginous Embolism Treated With Tenecteplase.

The neurologist·2026
Same journal

Cervical Artery Dissection and Chiropractic.

The neurologist·2026
See all related articles

Nerve agents cause severe poisoning by inhibiting acetylcholinesterase. Understanding nerve agent pathophysiology and treatment is vital for medical professionals to manage poisoning and prepare for chemical terrorism.

Area of Science:

  • Toxicology
  • Emergency Medicine
  • Neurology

Background:

  • Nerve agents are potent chemical warfare agents that inhibit acetylcholinesterase, leading to life-threatening cholinergic crisis.
  • Originally developed for military use, nerve agents pose a significant threat to civilian populations due to potential terrorist attacks.

Observation:

  • Acute nerve agent poisoning presents a complex clinical picture requiring prompt medical intervention.
  • Pyridostigmine bromide is approved for pretreatment against soman poisoning in military settings but has limited civilian application.

Findings:

  • Current civilian treatment protocols for acute nerve agent poisoning are largely adapted from military doctrine.
  • Effective management hinges on timely supportive care and appropriate antidotal administration.

Related Experiment Videos

Implications:

  • Neurologists must be proficient in nerve agent toxicology and treatment to manage poisoned patients.
  • Medical communities need neurologists as resources for preparedness and response to chemical terrorism involving nerve agents.