A novel approach to phylogenetic tree construction using stochastic optimization and clustering
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Updated: Jul 17, 2026

Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin
Published on: August 14, 2018
1Department of Computer Science, Nanjing University of Aeronautics and Astronautics, Nanjing, 210096, China. qllynne@nuaa.edu.cn
Background:
The problem of inferring the evolutionary history and constructing the phylogenetic tree with high performance has become one of the major problems in computational biology.
Results:
A new phylogenetic tree construction method from a given set of objects (proteins, species, etc.) is presented. As an extension of ant colony optimization, this method proposes an adaptive phylogenetic clustering algorithm based on a digraph to find a tree structure that defines the ancestral relationships among the given objects.
Conclusion:
Our phylogenetic tree construction method is tested to compare its results with that of the genetic algorithm (GA). Experimental results show that our algorithm converges much faster and also achieves higher quality than GA.
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