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Effects of an intrahospital exercise program intervention for children with leukemia
Alejandro F San Juan1, Steven J Fleck, Carolina Chamorro-Viña
1European University of Madrid, Madrid, Spain.
Medicine and Science in Sports and Exercise
|January 16, 2007
Summary
Supervised exercise, including resistance and aerobic training, significantly improved aerobic fitness, strength, and mobility in children undergoing acute lymphoblastic leukemia (ALL) treatment. Strength and mobility were well maintained during detraining.
Area of Science:
- Pediatric Oncology
- Exercise Physiology
- Rehabilitation Medicine
Background:
- Children undergoing treatment for acute lymphoblastic leukemia (ALL) often experience deconditioning.
- Supervised exercise programs may mitigate these effects and improve health outcomes.
Purpose of the Study:
- To assess the impact of a 16-week intrahospital supervised conditioning program (resistance and aerobic training) followed by 20 weeks of detraining.
- To evaluate changes in aerobic fitness, muscular strength, functional mobility, ankle range of motion, and quality of life (QOL) in children with ALL.
Main Methods:
- Seven children (5.1 ± 1.2 years) in the maintenance phase of ALL treatment participated.
- The program involved 3 weekly sessions of resistance and aerobic training for 16 weeks.
- Measurements included .VO2peak, ventilatory threshold (VT), muscular strength (6RM), functional mobility tests, ankle range of motion, and QOL.
Main Results:
- Significant improvements were observed in .VO2peak, VT, upper- and lower-body muscular strength, and functional mobility post-training (P < 0.05).
- Muscular strength was well maintained during detraining.
- .VO2peak, VT, and functional mobility showed partial retention during the detraining period.
Conclusions:
- Young children with ALL can safely engage in supervised aerobic and resistance training.
- The training program significantly enhances aerobic fitness, strength, and functional mobility.
- Strength and functional mobility are well-maintained post-training, while aerobic capacity shows partial retention during detraining.
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