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Updated: Jul 17, 2026

Retroductal Submandibular Gland Instillation and Localized Fractionated Irradiation in a Rat Model of Salivary Hypofunction
Published on: April 24, 2016
Oral complications of radiotherapy in the head and neck
Bruno Correia Jham1, Addah Regina da Silva Freire
1Faculdade de Odontologia, Universidade Federal de Minas Gerais, Brazil.
Unlabelled:
Radiotherapy is a treatment modality largely used for head and neck malignancies. However, high doses of radiation in large areas, including the oral cavity, maxilla, mandible and salivary glands may result in several undesired reactions. Mucositis, candidosis, disgeusia, radiation caries, osteoradionecrosis, soft tissue necrosis and xerostomia are some of radiotherapys complications.
Aim:
The aim of this study is to briefly review the side effects that may be seen in the oral cavity during or after radiotherapy treatment in the head and neck region. BASIC METHOD USED: Review of relevant literature.
Study Design:
Literature review.
Results:
Radiotherapy is still associated with several side effects, significantly affecting patients quality of life.
Conclusions:
A multidisciplinary treatment, including physicians, dentists, speech therapists, nutritionists, and psychologists, is the best alternative to minimize, or even prevent such reactions.
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