Related Experiment Video
Updated: Jul 17, 2026
Measuring Volatile and Non-volatile Antifungal Activity of Biocontrol Products
Published on: December 5, 2020
Growth inhibition of Trichophyton species by Pseudomonas aeruginosa
James Treat1, William D James, Irving Nachamkin
1Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.
Objective:
To assess the ability of Pseudomonas aeruginosa to inhibit the growth of Trichophyton mentagrophytes (TM) and Trichophyton rubrum (TR).
Design:
Pseudomonas aeruginosa, Escherichia coli, or Staphylococcus epidermidis were grown in co-culture with either TM or TR.
Setting:
An academic medical center.
Main Outcome Measures:
The total fungal units and hyphal-spore ratio were measured at days 1, 5, 10, and 15.
Results:
There was a 73% and 46% reduction of total fungal units and a final hyphal-spore ratio of 0.16 and 0.04, respectively, when TM and TR were co-cultured with P aeruginosa. The number of fungal units increased when TM and TR were cultured with E coli (28% and 42%, respectively), S epidermidis (13% and 18%, respectively), and control media (44% and 62%, respectively), and the hyphal-spore ratio increased to above 30 in the presence of S epidermidis, E coli, and control media.
Conclusion:
Pseudomonas aeruginosa exhibits growth inhibitory properties against TM and TR.
