[Immunologic indices in chronic pancreatitis and in its combination with other diseases of the digestive system]

Analysis of the immune system status of 200 patients with chronic pancreatitis has shown more marked immune shifts in the patients with the primary condition, who presented with high levels of immune complexes and autosensitization to pancreatic tissue. When pancreatitis was associated with intestinal abnormalities, T lymphocyte function was depressed, as was nonspecific defense of the body. In cases when chronic pancreatitis resulted from diseases of the bile duct, stomach, or duodenum, the findings evidenced high blood serum levels of immunoglobulins A, G, and M, and significant bacterial sensitization. These results may be useful in choosing immunocorrecting therapy.