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Related Experiment Video

Updated: Jul 17, 2026

2D-HPLC-MS Technology Combined with Molecular Network for the Identification of Components in Tibetan Medicine Aconitum pendulum

2D-HPLC-MS Technology Combined with Molecular Network for the Identification of Components in Tibetan Medicine Aconitum pendulum

Published on: December 8, 2023

Diterpenoid Alkaloids from Aconitum vilmorrianum.

L S Ding¹, Y Z Chen, F E Wu

¹Department of Chemistry, Lanzhou University, Lanzhou, 730000, People's Republic of China.

|June 1, 1991

Summary

A novel diterpenoid alkaloid, vilmorrianone, was isolated from Aconitum vilmorrianum. Its structure was confirmed using spectral data and X-ray diffraction, alongside four known alkaloids.

Area of Science:

Natural Product Chemistry
Phytochemistry
Organic Chemistry

Background:

Aconitum vilmorrianum is a plant species known for its potential medicinal properties.
Diterpenoid alkaloids represent a significant class of natural products with diverse biological activities.

Purpose of the Study:

To isolate and characterize new chemical constituents from Aconitum vilmorrianum.
To elucidate the structure of a novel diterpenoid alkaloid.

Main Methods:

Isolation of compounds using chromatographic techniques.
Structure elucidation employing spectroscopic methods (NMR, MS).
Confirmation of structure via X-ray diffraction analysis.

Main Results:

Related Experiment Videos

Last Updated: Jul 17, 2026

2D-HPLC-MS Technology Combined with Molecular Network for the Identification of Components in Tibetan Medicine Aconitum pendulum

2D-HPLC-MS Technology Combined with Molecular Network for the Identification of Components in Tibetan Medicine Aconitum pendulum

Published on: December 8, 2023

A new diterpenoid alkaloid, named vilmorrianone (1), was successfully isolated.

The chemical structure of vilmorrianone was determined through comprehensive spectral analysis.

X-ray diffraction analysis provided definitive structural confirmation.

Four known diterpenoid alkaloids were also identified from the plant extract.

Conclusions:

The study successfully identified a new diterpenoid alkaloid, vilmorrianone, from Aconitum vilmorrianum.
The structural elucidation provides valuable data for understanding the chemical diversity of Aconitum species.