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Updated: Jul 17, 2026

Oxygenation-sensitive Cardiac MRI with Vasoactive Breathing Maneuvers for the Non-invasive Assessment of Coronary Microvascular Dysfunction
Published on: August 17, 2022
[Severe hyperventilation as a differential diagnosis of acute coronary syndrome]
Thomas Feldskov1, Anne-Bolette J Gude, Michael V Højgaard
1Bispebjerg Hospital, Kardiologisk Afdeling Y. feldskov@mail.tele.dk
Abstract:
We report a case where a 30-year-old, otherwise healthy female was admitted to hospital with symptoms of hyperventilation, including chest discomfort and an abnormal ECG showing ST depressions and T-wave inversions. The ECG changes disappeared spontaneously during the next 24 hours as the patient was calmed down. A few weeks after discharge, the ECG changes were partially reproduced during a six-minute hyperventilation test. It is worth remembering that severe hyperventilation can cause ECG changes similar to those seen in acute coronary syndrome.
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