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Updated: Jul 17, 2026

High Resolution 3D Imaging of Ex-Vivo Biological Samples by Micro CT
Published on: June 21, 2011
Improvement of spatial resolution in the longitudinal direction for isotropic imaging in helical CT
Shinsuke Tsukagoshi1, Takamasa Ota, Misako Fujii
1CT Systems Development Department, Toshiba Medical Systems Corporation, 1385 Shimoishigami Otawara-Shi, Tochigi 324-8550, Japan. shinsuke.tsukagoshi@toshiba.co.jp
Abstract:
Experiments were conducted to confirm the isotropic spatial resolution of multislice CT with a 0.5 mm slice thickness. Isotropic spatial resolution means that the spatial resolution in the transaxial plane (X-Y plane) and that in the longitudinal direction (Z direction) are equivalent. To obtain point spread function (PSF) values in the X-Y-Z directions, three-dimensional voxel data were obtained by helical scanning of a bead phantom. The modulation transfer function (MTF) values were then obtained by three-dimensional Fourier transform of the PSF. Evaluation of the spatial resolution in the X-Y-Z directions by the MTF values showed that the spatial resolution in the Z direction does not depend on the reconstruction kernel used. It was also found that the spatial resolution in the Z direction, as compared with that in the X-Y plane, is superior with the standard kernel for the abdomen and is inferior with the high-definition kernel for the ears/bones. By performing sharpening filter processing in the Z direction with a high-definition kernel, comparable spatial resolution could be obtained in the X-Y-Z directions. It was confirmed that adjusting the spatial resolution in the Z direction with the reconstruction kernel used is an effective method for isotropic imaging.
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