[The spleno-cytotoxic test--an indicator of toxemia in oncologic patients]

Biologic integral methods for indication of blood toxicity, the migration activity of intact donor leukocytes in agar, and the splenocytotoxic test were used in radiotoxemia assessment in 62 oncologic patients with radiation reactions and in studies on the efficacy of detoxifying therapy with polyvisoline, a new blood substitute, in 25 subjects. Both the methods for studies of the blood serum toxicity were found sufficiently informative and unsophisticated, but the splenocytotoxic test proved to be more sensitive, simple, and rapid.