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"Pseudosarcoma" in a pregnant woman

Amarjit Anand1, Eva Maria Tsapakis, Ali A Narvani

  • 1Royal Free and University College London Hospitals, Royal National Orthopaedic Hospital, Bone Tumour Unit, Brockley Hill, Stanmore, Middlesex, HA7 4L, UK. amarjitanand@doctors.org.uk

World Journal of Surgical Oncology
|January 19, 2007
PubMed
Abstract

Insights

Intravascular fasciitis (IVF), a rare benign condition, involves myofibroblastic proliferation in blood vessels. Pregnancy may influence the development of this condition, as seen in a case report.

Area of Science:

  • Vascular Pathology
  • Histopathology
  • Reproductive Medicine

Background:

  • Intravascular fasciitis (IVF) is a rare benign condition characterized by myofibroblastic proliferation involving arteries and/or veins.
  • It is a distinct variant of nodular fasciitis, differing by the presence of vascular invasion.
  • Only 26 cases of IVF have been previously reported in the literature.

Purpose of the Study:

  • To report a unique case of intravascular fasciitis (IVF) in a pregnant patient.
  • To explore the potential role of pregnancy-related hormonal changes in the pathogenesis of IVF.

Main Methods:

  • Case report of a 16-week pregnant patient with IVF.
  • Clinical and histological evaluation of the lesion affecting the hypothenar eminence and ulnar artery.

Main Results:

  • The case presented a reactive myofibroblastic proliferation involving the ulnar artery in the hypothenar eminence.
  • Histological features mimicked malignancy, highlighting diagnostic challenges.

Conclusions:

  • The vascular involvement in IVF can be mistaken for malignancy, leading to misdiagnosis of this benign condition.
  • Hormonal fluctuations during pregnancy may contribute to the development of intravascular fasciitis.

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